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Dementia Dangers: How Hearing Loss Rewires the Brain


Dementia Brain Hearing Headache Art

Researchers found that hearing loss in older adults is linked to brain changes in areas related to sound processing and executive functions, potentially increasing the risk of dementia. Protective measures such as hearing aids and avoiding loud noises are suggested to mitigate this risk.

Increased dementia risk associated with hearing impairment may come from compensatory brain changes.

Hearing loss affects more than 60 percent of adults aged 70 and older in the United States and is known to be related to an increased risk of dementia. The reason for this association is not fully understood.

Research on Hearing Impairment and Brain Changes

To better understand the connection, a team of University of California San Diego and Kaiser Permanente Washington Health Research Institute researchers employed hearing tests and magnetic resonance imaging (MRI) to determine whether hearing impairment is associated with differences in specific brain regions.

Study Findings

In the November 21, 2023 issue of the Journal of

Preventive Measures and Study Methodology

“If so, interventions that help reduce the cognitive effort required to understand speech — such as the use of subtitles on television and movies, live captioning or speech-to-text apps, hearing aids, and visiting with people in quiet environments instead of noisy spaces — could be important for protecting the brain and reduce the risk of dementia.”

McEvoy designed and led the study while at UC San Diego, in collaboration with Reas and UC San Diego School of Medicine investigators who gathered data from the Rancho Bernardo Study of Health Aging, a longitudinal cohort study of residents of the Rancho Bernardo suburb in San Diego that launched in 1972. For this analysis, 130 study participants underwent hearing threshold tests in research clinic visits between 2003 and 2005 and subsequently had MRI scans between 2014 and 2016.

Conclusion and Recommendations

The results of the study show that hearing impairment is associated with regionally specific brain changes that may occur due to sensory deprivation and to the increased effort required to understand auditory processing stimulations.

“The findings emphasize the importance of protecting one’s hearing by avoiding prolonged exposure to loud sounds, wearing hearing protection when using loud tools and reducing the use of ototoxic medications,” said co-author Emilie T. Reas, Ph.D., assistant professor at the UC San Diego School of Medicine.

Reference: “Elevated Pure Tone Thresholds Are Associated with Altered Microstructure in Cortical Areas Related to Auditory Processing and Attentional Allocation” by Linda K. McEvoy, Jaclyn Bergstrom, Donald J. Hagler Jr, David Wing and Emilie T. Reas, 21 November 2023, Journal of Alzheimer’s Disease.
DOI: 10.3233/JAD-230767

Co-authors include: Jaclyn Bergstrom, Donald J. Hagler Jr, David Wing, and Emilie T. Reas, all of UC San Diego.

This research was funded, in part, by the National Institute on Aging (R00AG057797, R01AG077202, R01AA021187) and the American Federation for Aging Research/McKnight Foundation (311122-00001). Data collection for the Rancho Bernardo Study of Healthy Aging was provided primarily by the





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